In Vivo Services for New Drug Modalities
With bi-coastal AAALAC accredited rodent facilities, Meadowhawk expedites preclinical drug research. Our scientific staff is well versed in R&D stage non-GLP in vivo studies, providing a comprehensive range of studies, from initial evaluations like PK exposure screening and efficacy/mechanism exploration to in-depth analyses including PK/PD correlation, dose range finding, and tissue distribution.
Equipped with both LC/MS and immunoanalytical techniques, we deliver a complete picture of your test article, supporting a wide range of modalities, including new chemical entities (NCEs) and their modifications/delivery systems, various biologics (peptides, proteins, antibodies), antibody-drug conjugates (ADCs), gene and cell therapy delivery systems (lipid nanoparticles).
Equipped with both LC/MS and immunoanalytical techniques, we deliver a complete picture of your test article, supporting a wide range of modalities...
Talk to a ScientistAAALAC Accredited Facilities in Boston & San Francisco focused on animal welfare and compliance with IACUC oversight and protocol guidelines.
Local Courier Service to expedite TA and sample logistics to better serve clients on the east and west coasts.
A Certified and Trained Staff with years of experience in the pharmacology and pharmacokinetic studies dosing various test articles.
A Dedicated Study Director to provide inputs and monitor study execution to ensure streamlined communication.
In Vivo Imaging System (MA) providing a noninvasive, sequential monitoring of compounds in live animals using bioluminescence or fluorescence. Ex vivo tissue imaging also available
Test Article to Results in 5 Business Days
Performing both stand alone in-life studies and as well as integrated studies, Meadowhawk offers standard animal strains (CD1, C57bl/6, Sprague Dawley, and Wistar Han) as well as client specific species/strains – working side-by-side with LCMS and IA teams to deliver results in as little as 5 business days.
Using major rodent suppliers or client dedicated colony rodents, upon proper health check and acclimation we conduct in-life and bioanalysis together to provide specific PK and PK/PD correlated study data. Samples are collected using multiple administration methods (IV, PO, SC, IP, IM, etc.) and include blood-derived samples (whole blood, plasma, serum), cerebrospinal fluid, bile, urine and all types of tissues, including liver, lung, heart, kidney, intestines, muscle, fat, and more.
In the spirit of collaboration and transparency, clients are welcome to monitor or observe their studies on site from dose administration through sample collection.
How AAALAC Accredited Rodent Vivarium Can Advance R&D Programs
Cutting through the slow process of preclinical drug development is essential, especially for start-ups. See how Meadowhawk delivers dose to data results in as little as 5 days, allowing researchers to make quicker decisions and optimize their drug development pipeline.
In Vivo Case Study
In order to advance drug R&D, accurate and fast experimental results are key to...
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