Service Types

Discovery Bioanalysis LCMS

Optimizing Data Quality and Speed with Custom-Designed Assays

Meadowhawk has deep experience and expertise in non-regulated liquid chromatography mass spectrometry (LCMS) discovery bioanalysis. Taking a two pronged approach, we use diagnostic probes and a 3-tier assay design to analyze different drug modalities in biofluids as well as a variety of tissues from rodent to human.

Whether quantifying small organic molecules or more complex molecule types such as peptides, proteins, nucleotides, lipid nanoparticles and payload of ADCs, our Research Grade Assays give you the data you need, when you need it.

Our Research Grade Assays give you the data you need, when you need it.

Talk to a Scientist
  • Client dedicated, senior scientific team supported by state-of-the-art instruments

  • Three fit-for-purpose assay tier levels including screening, lead optimization and IND-enabled

  • Specialized instruments and diagnostic tools providing critical discovery study data quality insights

  • A wide range of drug modalities from conventional small organic molecules to complex ADCs

  • Local courier service to simplify logistics and facilitate the fastest study starts in the area.

Take The Shortest Path Possible

Take The Shortest Path Possible

With decades of non-regulated LCMS discovery bioanalysis experience, our scientists serve as your dedicated, single point of contact, keeping studies on schedule & facilitating effective communication. Our fit-for-purpose approach provides flexibility to meet discovery stage requests across drug modalities and endogenous biomarkers. Using a 3-tier approach, we serve a full range of bioanalysis (BA) needs, including screening, optimization, and IND-enabling. In addition, we also support biodistribution requests using matrix matching and surrogate matrix approaches.

To expedite compound and sample logistics, we provide a local courier service that often picks up within 48 hours of your request.

FAQs

How does Meadowhawk tailor LC-MS assays to different stages of discovery?

Meadowhawk deploys LC-MS assays to the decision your discovery program needs to make. Rather than applying late-stage assay requirements to every early study, we use a fit-for-purpose approach that aligns sensitivity, selectivity, calibration range, precision,
matrix evaluation, stability, and documentation with your program stage—from rapid candidate screening to more rigorous preclinical bioanalysis.

What drug modalities can Meadowhawk support with LC-MS bioanalysis?

Can you analyze very small samples and challenging biological matrices?

How does Meadowhawk deliver rapid discovery data without compromising scientific quality?

When would you use quantitative LC-MS/MS versus high-resolution MS?

Why involve the LC-MS scientist before the in vivo study starts?

Let's Go Our Own Way.

Tell us about your LCMS project.